Recombinant Expression and Stapling of a Novel Long-Acting GLP-1R Peptide Agonist
Owing to their pleiotropic metabolic benefits, glucagon-like peptide-1 receptor (GLP-1R) agonists have been successfully utilized for KNIT TOPS3/4 SLVSCOOP treating metabolic diseases, such as type 2 diabetes and obesity.As part of our efforts in developing long-acting peptide therapeutics, we have previously reported a peptide engineering strategy